Tissue recovery: Protein helps injured livers to regenerate


Researchers at the Texas A&M Health Science Center’s Institute of Biosciences and Technology in Houston’s Texas Medical Center have uncovered a new mechanism for protecting the genetic integrity of actively dividing cells in the liver – a finding that could improve treatment and recovery in adult tissue or organs after injury. The study is available online and in the December edition of Hepatology, the official Journal of the American Association for the Study of Liver Diseases.

“Stem cells and cancer cells have the unique ability to maintain an extended reproductive lifespan compared to most other cells in the body,” explains Robert Tsai, M.D., Ph.D., associate professor in the Texas A&M IBT Center for Cancer and Stem Cell Biology and principal investigator of the study. “We applied this understanding to adult tissue regeneration to discover why this proliferating trait is not present in all tissue.”

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