Center for Biological Nuclear Magnetic Resonance

Center for Biological Nuclear Magnetic Resonance

Research efforts of the Center for Biological Nuclear Magnetic Resonance are directed toward a more complete understanding of the fundamental principles involved in enzyme-catalyzed chemistry and protein structure. The acquisition of this information provides the framework for the redesign of these complex molecules in a concerted effort to exploit the properties of enzyme active sites for a variety of chemical and medicinal uses. The techniques used solve these problems including steady-state and stopped-flow kinetics, nuclear magnetic resonance spectroscopy (NMR), electron paramagnetic resonance (EPR), x-ray crystallography, chemical synthesis of inhibitors and novel substrates, and site-directed mutagenesis for the construction of new proteins with unique catalytic properties.

College of Science
Contact: Frank Raushel
Phone: 979.845.3373